Scrobbling is the Last.fm mechanic that tells its listeners what songs they play most often, which songs they like the most, how much they've played an artist over a certain amount of time and which friends have similar tastes.
The 60 billion milestone was reached at 6.26am this morning with Gaga joining the likes of Bob Dylan, James Blunt and Linkin' Park in the scrobble hall of fame.
Dylan's 'Blowin' In The Wind' marked Last.fm's 50 billionth scrobble while James Blunt took the 10 billionth scrobble in 2007 with '1973' and Linkin' Park were responsible for the billionth scrobble in 2005 with 'Pushing Me Away'.
"Hitting 60 billion scrobbles reinforces our position as the global leader in intelligent data on music discovery and recommendations within the broader music ecosystem," said Last.FM's VP of product and marketing Matthew Hawn.
"Reaching this figure is testament to the passion and enthusiasm demonstrated by our users."